Preservatives in artificial tears: Assessing impact on dry eye symptoms

Our findings suggest that BAK-preserved AT may worsen DED symptoms. We found higher ORs for experiencing itching and blurred vision as well as a tendency towards experiencing a higher number of symptoms when using BAK-preserved AT compared to preservative-free AT. Further longitudinal studies with additional questions on AT usage and clinical assessments are needed to validate these findings and optimize AT formulations for safer, effective DED management.

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Publication Details

Journal
Acta Ophthalmologica
Published
2025-04-22
DOI
https://doi.org/10.1111/aos.17500
Citations
1
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
1.88

Funders

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article

Preservatives in artificial tears: Assessing impact on dry eye symptoms

Miriam Kolko, Jens Rovelt Andreasen, Astrid Dissing Sjö, Simone Ahrenberg
1 citations
Acta Ophthalmologica
Ocular Surface and Contact Lens
1.88
article

Preservatives in artificial tears: Assessing impact on dry eye symptoms

Miriam Kolko, Jens Rovelt Andreasen, Astrid Dissing Sjö, Simone Ahrenberg
article en
1 citations

Abstract

Our findings suggest that BAK-preserved AT may worsen DED symptoms. We found higher ORs for experiencing itching and blurred vision as well as a tendency towards experiencing a higher number of symptoms when using BAK-preserved AT compared to preservative-free AT. Further longitudinal studies with additional questions on AT usage and clinical assessments are needed to validate these findings and optimize AT formulations for safer, effective DED management.

Acta OphthalmologicaVol. 103(7)
University of Copenhagen (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK)
Velux Fonden, Synoptik-Fonden, Rigshospitalet, A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal, Copenhagen Graduate School for Nanoscience and Nanotechnology
Good health and well-being
Openalex Percentile: Top 17%
Ocular Surface and Contact Lens
1.88
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