Unraveling the Causal Links Between Immune Traits and Hepatocellular Carcinoma: Insights From a Bi-Directional Mendelian Randomization Study
This study provides strong evidence of genetic links between systematic immune cell profiles and HCC, shedding light on the mechanisms underlying its onset and progression. These findings identify potential immune biomarkers for early diagnosis and immune-targeted therapies.
Authors
- Xiaonan Xiang (ORCID: https://orcid.org/0009-0001-8744-6819)
- G Q Wang (ORCID: https://orcid.org/0009-0001-0346-3399)
- Jianguo Wang (ORCID: https://orcid.org/0000-0002-8030-2900)
- Jie Li (ORCID: https://orcid.org/0000-0001-7882-4091)
Institutions
- Sir Run Run Shaw Hospital (CN)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Zhejiang Provincial People's Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
- Hangzhou Medical College (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- The Turkish Journal of Gastroenterology
- Published
- 2025-04-21
- DOI
- https://doi.org/10.5152/tjg.2025.24558
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00