PPARγ Activates Autophagy by Suppressing the PI3K–AKT1–FOXO3 Signaling Pathway and thus Alleviates Hepatic Ischemia-Reperfusion Injury
Peroxisome proliferator activated receptor gamma inhibited the PI3K-AKT1-FOXO3 signaling pathway, which in turn activated autophagy to alleviate HIRI.
Authors
- Hengguan Cui
- Bin Yan (ORCID: https://orcid.org/0000-0002-5952-5982)
- Weixing Shen (ORCID: https://orcid.org/0000-0002-6454-3296)
- Xinyu Liu (ORCID: https://orcid.org/0000-0002-2388-844X)
- Xian-qing Song (ORCID: https://orcid.org/0009-0002-0281-5716)
Institutions
- Fudan University (CN)
- Zhongshan Hospital (CN)
- Baotou Central Hospital (CN)
- Shenzhen Bao'an District People's Hospital (CN)
Publication Details
- Journal
- The Turkish Journal of Gastroenterology
- Published
- 2025-04-21
- DOI
- https://doi.org/10.5152/tjg.2025.24529
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35