Effect of Hyperbaric Oxygen Therapy Dose on Post-Replantation of the Distal Phalanx of Digiti II Manus Sinistra

Finger replantation in adults requires a more extended healing period and is at risk of failure. Giving hyperbaric oxygen therapy (HBOT) at the correct dose can speed healing, reducing the risk of failure. A case involved a 32-year-old woman after replantation of the distal phalanx of digiti II manus sinistra of the patient who experienced cyanosis and necrosis. This report analyzes the relationship between HBOT dose and accelerated stimulation of growth factors that can improve the wound healing process. Replantation refers to the reconnection of an amputated body part to its anatomical structure to restore the function of the injured part. The outcome depends on the dose of HBOT, the patient's intrinsic factors, and the nature of the injury. Giving HBOT once a day, in this case, was not effective because the patient's fingertips became more cyanotic, and necrosis increased. Providing the correct dose of HBOT twice a day accelerates overcoming hypoxia. It helps successfully heal wounds through angiogenesis, collagen formation, and epithelialization, so new tissue growth is expected to accelerate.

Publication Details

Journal
Journal of Liaquat University of Medical & Health Sciences
Published
2025-03-30
DOI
https://doi.org/10.22442/jlumhs.2025.01145
Primary Topic
Reconstructive Surgery and Microvascular Techniques
Type
article
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article

Effect of Hyperbaric Oxygen Therapy Dose on Post-Replantation of the Distal Phalanx of Digiti II Manus Sinistra

Journal of Liaquat University of Medical & Health Sciences
Reconstructive Surgery and Microvascular Techniques
article

Effect of Hyperbaric Oxygen Therapy Dose on Post-Replantation of the Distal Phalanx of Digiti II Manus Sinistra

article en

Abstract

Finger replantation in adults requires a more extended healing period and is at risk of failure. Giving hyperbaric oxygen therapy (HBOT) at the correct dose can speed healing, reducing the risk of failure. A case involved a 32-year-old woman after replantation of the distal phalanx of digiti II manus sinistra of the patient who experienced cyanosis and necrosis. This report analyzes the relationship between HBOT dose and accelerated stimulation of growth factors that can improve the wound healing process. Replantation refers to the reconnection of an amputated body part to its anatomical structure to restore the function of the injured part. The outcome depends on the dose of HBOT, the patient's intrinsic factors, and the nature of the injury. Giving HBOT once a day, in this case, was not effective because the patient's fingertips became more cyanotic, and necrosis increased. Providing the correct dose of HBOT twice a day accelerates overcoming hypoxia. It helps successfully heal wounds through angiogenesis, collagen formation, and epithelialization, so new tissue growth is expected to accelerate.

Journal of Liaquat University of Medical & Health SciencesVol. 24(01)
Openalex Percentile: Top 86%
Reconstructive Surgery and Microvascular Techniques
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Effect of Hyperbaric Oxygen Therapy Dose on Post-Replantation of the Distal Phalanx of Digiti II Manus Sinistra · Journal of Liaquat University of Medical & Health Sciences (2025) | TGRS Research Map | TGRS