Efficacy of Doramectin AVZ against parasitic diseases of sheep

Determine the therapeutic efficacy of Doramectin AVZ against itch mites, ixodid ticks and parasitic insects in sheep. In August 2024, in the territory of the Izobilnensky district of the Stavropol Territory, 3 groups of sheep with a confirmed clinical diagnosis were formed in a peasant farm enterprise: psoroptosis, tick infestation and melophagosis. The first group of sheep was treated with Doramectin AVZ at a dose of 1 ml of the preparation per head. The second group was treated with Meradoc at a dose of 1 ml of the preparation per head. The third group was a control and was not treated. The first and second groups were treated by subcutaneous administration. All experimental groups of sheep were kept in isolation. The therapeutic efficacy of Doramectin AVZ and Meradoc was assessed by clinical examination and skin microscopy for the presence of itch mites (Psoroptesovis), ixodid ticks (Hyalomma and Dermacentor) and parasitic insects (Melophagus ovinus) before the experiment and after 1, 3, 7, 10, 14, 21 and 28 days in the experimental of sheep. It was found that Doramectin AVZ and Meradoc, after double treatment at a dose of 1 ml per head, showed therapeutic activity (protection) of sheep against the causative agents of psoroptosis, tick infestation and melophagosis for 28 days after double treatment with an interval of 10 days.