Multimetric MRI Captures Early Response and Acquired Resistance of Pancreatic Cancer to KRAS Inhibitor Therapy
Multiparametric MRI provides early biological insights of cancer and stromal responses to KRASi treatment and sets the stage for testing the utility of these clinically ready MRI methods in patients receiving KRASi therapy.
Authors
- Mamta Gupta (ORCID: https://orcid.org/0000-0003-0928-1104)
- Stephen Pickup (ORCID: https://orcid.org/0000-0002-7016-8648)
- Emma E. Furth (ORCID: https://orcid.org/0000-0002-9309-985X)
- Quy Cao (ORCID: https://orcid.org/0000-0002-6204-1305)
- Ben Z. Stanger (ORCID: https://orcid.org/0000-0003-0410-4037)
- Samantha B. Kemp (ORCID: https://orcid.org/0000-0002-1505-4015)
- Margo Orlen (ORCID: https://orcid.org/0000-0002-9834-6282)
- Rong Zhou (ORCID: https://orcid.org/0000-0003-4018-381X)
- Cynthia Clendenin (ORCID: https://orcid.org/0000-0003-4535-2088)
- Fang Liu (ORCID: https://orcid.org/0000-0003-2922-4414)
- Hoon Choi (ORCID: https://orcid.org/0000-0003-0064-5290)
- Mark A. Rosen (ORCID: https://orcid.org/0000-0002-1581-0220)
Institutions
- University of Pennsylvania (US)
- Philadelphia University (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-4049
- Citations
- 5
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 5.23