Maternal age is associated with apoptotic gene abundance patterns in blastocoel fluid-conditioned media from euploid embryos: a pilot study
This study uncovered differential apoptotic gene abundance associated with maternal age by assessing blastocoel fluid-conditioned media from euploid blastocysts. These unique abundance patterns may provide insight into the regulation of apoptosis in embryos from women of advanced maternal age, and how this signaling pathway may impact implantation outcomes.
Authors
- Hayes C. Lanford (ORCID: https://orcid.org/0000-0002-2358-4227)
- Dieu Thao Nguyen
- Carson Collins
- Richard J. Kordus (ORCID: https://orcid.org/0000-0001-6921-6422)
- Lisa Green (ORCID: https://orcid.org/0009-0005-0532-5941)
- T. Arthur Chang (ORCID: https://orcid.org/0000-0002-3040-9400)
- Angel Earle
- Renée J. Chosed (ORCID: https://orcid.org/0000-0002-0442-0833)
- Eleanor Petyak
- Alyssa Clay‐Gilmour (ORCID: https://orcid.org/0000-0001-9998-4879)
- William E. Roudebush (ORCID: https://orcid.org/0000-0003-1746-455X)
- Kayla Vaillant
- Hannah Archer
Institutions
- Prisma Health (US)
- University of South Carolina (US)
- The University of Texas at San Antonio Health Science Center (US)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1007/s10815-025-03485-7
- Citations
- 2
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- University of South Carolina