A New Score for Metabolic Age in Type 2 Diabetes Mellitus: Physical Rating Score

<b>Background</b>: Metabolic age (met-age), a risk marker, may vary within the same chronological age group. Its association with chronological age, waist/height ratio, obesity degree, body mass index (BMI), and physical rating score (PRS)-risk factors for type 2 diabetes-remains unexplored. <b>Methods</b>: A total of 122 type 2 diabetes patients (50 males, 72 females) were analyzed. Bioimpedance measurements were taken using the Tanita MC-780MA, alongside anthropometric data. Variables were compared, and correlations with met-age were assessed. <b>Results</b>: The met-age-chronological age difference was higher in females with type 2 diabetes (<i>p</i> < 0.001). Females also had higher BMI, obesity degree, fat mass, and waist/height ratio (<i>p</i> < 0.05), but lower waist/hip ratio (<i>p</i> < 0.001). Males showed higher PRS, muscle mass, and fat-free mass (<i>p</i> < 0.001). Met-age positively correlated with chronological age and negatively with PRS in both sexes (<i>p</i> < 0.05). According to the linear regression model, in females, the met-age was influenced positively by chronological age and waist/height ratio and negatively by PRS (R² = 0.983). In males, it was positively influenced by chronological age, obesity grade, and BMI, but negatively by PRS (R² = 0.974). <b>Conclusions</b>: Met-age correlates with chronological age and PRS in type 2 diabetes patients. It increases with advancing age and lower PRS, with waist/height ratio impacting females and BMI/obesity degree affecting males.