Comparative Analysis of Biological Aging and Inflammatory Profiles in Adult Spinal Deformity Patients Between Japan and the United States
JPs are biologically younger than their US counterparts, potentially due to lifestyle factors. JP ASDs exhibit accelerated biological aging compared with the norm cohort, highlighting the impact of ASD on aging. Elevated systemic inflammation in ASDs underscores the importance of managing inflammatory processes.
Authors
- Justin S. Smith (ORCID: https://orcid.org/0000-0001-7314-7896)
- Christopher Pearson Ames (ORCID: https://orcid.org/0000-0003-2618-3098)
- Mitsuru Yagi (ORCID: https://orcid.org/0000-0002-2324-3780)
- Christopher I. Shaffrey (ORCID: https://orcid.org/0000-0001-9760-8386)
- Michael P. Kelly (ORCID: https://orcid.org/0000-0001-6221-7406)
- Shay R. Bess (ORCID: https://orcid.org/0000-0002-9697-8999)
- Virginie Lafage (ORCID: https://orcid.org/0000-0002-0119-7111)
- Frank J. Schwab
- Naobumi Hosogane
Institutions
- Apple (Israel) (IL)
- Duke University (US)
- University of California, San Francisco (US)
- Kyorin University (JP)
- University of Virginia Health System (US)
- Lenox Hill Hospital (US)
- Rady Children's Hospital-San Diego (US)
- NOF Corporation (Japan) (JP)
- Twin Cities Spine Center (US)
- Curtiss-Wright (United States) (US)
- Neurological Surgery (US)
- International University of Health and Welfare (JP)
Publication Details
- Journal
- Spine
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1097/brs.0000000000005370
- Primary Topic
- Scoliosis diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00