Application of Neoadjuvant Docetaxel plus Cisplatin in Early-Stage Triple-Negative Breast Cancer (HELEN-001): Results from a Phase II Trial

The TP regimen demonstrated significantly improved pCR rates with a manageable toxicity profile, suggesting the potential benefit of taxane plus platinum regimens in patients with TNBC.

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Publication Details

Journal
Clinical Cancer Research
Published
2025-04-21
DOI
https://doi.org/10.1158/1078-0432.ccr-25-0289
Citations
2
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
1.87
Controls
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article

Application of Neoadjuvant Docetaxel plus Cisplatin in Early-Stage Triple-Negative Breast Cancer (HELEN-001): Results from a Phase II Trial

Lianfang Li, Xiuchun Chen, Armando Orlandi, Chongjian Zhang et al.
2 citations
Clinical Cancer Research
Breast Cancer Treatment Studies
1.87
article

Application of Neoadjuvant Docetaxel plus Cisplatin in Early-Stage Triple-Negative Breast Cancer (HELEN-001): Results from a Phase II Trial

Lianfang Li, Xiuchun Chen, Armando Orlandi, Chongjian Zhang, Fernando Hernánz, Xinlan Liu, Haiquan Jia, Qingxin Xia, Naohiro Ishii, Xianfu Sun, Min Yan, Chengzheng Wang, Geok Hoon Lim, Zhenzhen Liu, Jianghua Qiao, Yueqing Feng, Dechuang Jiao, Yong Zhou, Miao Deng, Zhenduo Lu, Mingde Ma
article en
2 citations

Abstract

The TP regimen demonstrated significantly improved pCR rates with a manageable toxicity profile, suggesting the potential benefit of taxane plus platinum regimens in patients with TNBC.

Clinical Cancer ResearchVol. 31(13)
Universidad de Cantabria (ES), Henan University of Science and Technology (CN), Agostino Gemelli University Polyclinic (IT), Zhengzhou University (CN), Henan University Huaihe Hospital and Huaihe Clinical Institute (CN), Marqués de Valdecilla University Hospital (ES), KK Women's and Children's Hospital (SG), Duke-NUS Medical School (SG), Ningxia Medical University (CN), First Affiliated Hospital of Henan University of Science and Technology (CN), Ningxia Medical University General Hospital (CN), Henan Cancer Hospital (CN), Xinxiang Central Hospital (CN), Anyang Tumor Hospital (CN), International University of Health and Welfare (JP)
Good health and well-being
Openalex Percentile: Top 15%
Breast Cancer Treatment Studies
1.87
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