Multicentric lymphomas in goats (<i>Capra hircus</i>): Clinical manifestations, therapeutic modalities and pathological characteristics

Abstract Two cases of sporadic multicentric lymphomas with mediastinal masses in goats are documented. The first case involved a 3.5‐year‐old male goat. Ultrasound imaging revealed an enlarged right perirenal lymph node, which was confirmed as lymphoma through incisional biopsy and cytopathological analysis. Despite treatment, the goat succumbed to the disease within 44 days. At postmortem examination, in the mediastinal region, a mass measuring 25.0 × 7.0 × 7.0 cm was identified. The diagnosis of multicentric diffuse large B‐cell lymphoma was confirmed through histopathology and PAX‐5 immunophenotyping. The second case involved a 2.0‐year‐old lactating goat, which presented with enlarged prescapular lymph nodes upon clinical examination and a mass in the cranio‐ventral thoracic region, as detected by ultrasound. Due to local circumstances, euthanasia was performed. At postmortem examination, in the mediastinal region, a mass measuring 11.0 × 6.0 cm was identified. This goat was diagnosed with multicentric T‐cell lymphoma based on histopathology and CD3 immunopositivity.