Visible-Light-Mediated Addition Reactions of Sulfur-Containing Reagents with α-Trifluoromethyl Alkenes
Herein, we described the addition reactions of sulfur-containing reagents (sodium sulfinates, dithiosulfonates) with α-trifluoromethyl alkenes under visible light. A series of trifluoromethyl sulfonates were synthesized via the visible-light-induced radical addition reaction of sodium sulfinates and α-trifluoromethyl alkenes to obtain protons from the solvent. A series of dithiosulfonated derivatives were synthesized via visible-light-induced bifunctionalization reaction of α-trifluoromethyl alkenes with dithiosulfonates.This strategy has the advantages of mild reaction conditions, good substrate universality and high yield up to 99% yield.
Authors
- Shun‐Yi Wang (ORCID: https://orcid.org/0000-0002-8985-8753)
- Yi‐Rong Chen (ORCID: https://orcid.org/0000-0002-4307-3002)
- Weidong Rao (ORCID: https://orcid.org/0000-0002-6088-7278)
- Daopeng Sheng
- Shusu Shen (ORCID: https://orcid.org/0000-0003-2307-999X)
- Ping Song (ORCID: https://orcid.org/0000-0002-5558-9890)
- Jiahui Han (ORCID: https://orcid.org/0000-0002-3999-751X)
Institutions
- Nanjing Forestry University (CN)
- Suzhou University of Science and Technology (CN)
- Electronics Testing Center (TW)
- Laboratoire de Synthèse Organique (FR)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1021/acs.joc.5c00396
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cyrus Tang Foundation
- National Natural Science Foundation of China
- Jiangsu Provincial Department of Education
- Soochow University
- Priority Academic Program Development of Jiangsu Higher Education Institutions