Sinonasal Glomangiopericytoma- A Rare Sinonasal Neoplasm

Glomangiopericytoma of the sinonasal type is a rare sinonasal soft tissue tumor of low malignant potential. Its nosologic nature was controversial after it was first reported by Stout and Murray in 1942, who termed it as sinonasal haemangiopericytoma. It behaves very indolently as compared to its soft tissue counterparts, and now its cell of origin is known to be a perivascular modified glomus-like cell with myoid features. Clinically, it has many mimics ranging from inflammatory nasal polyps to epithelial neoplasms and vascular tumors. Here, we report a case in a 52-year-old male patient who presented with epistaxis and sinonasal polypoid mass. CT/CECT showed a polypoid lesion involving the right nasal cavity between the right middle turbinate and bony nasal septum with the possibility of a small mucosal nasal polyp. Total resection was performed by endoscopic nasal route. On histopathology and immunohistochemical examination, it was diagnosed as sinonasal glomangiopericytoma (GPC). We discuss the histology features and differentials to help in the diagnosis of this rare nasal neoplasm that presents with common symptoms of epistaxis diagnosis.

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Publication Details

Journal
Central India Journal of Medical Research
Published
2025-04-18
DOI
https://doi.org/10.58999/cijmr.v4i01.213
Primary Topic
Soft tissue tumor case studies
Type
article
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article

Sinonasal Glomangiopericytoma- A Rare Sinonasal Neoplasm

Kavita Jain, Gauri Shukla, Priti Sharma, Rajeev Gupta et al.
Central India Journal of Medical Research
Soft tissue tumor case studies
article

Sinonasal Glomangiopericytoma- A Rare Sinonasal Neoplasm

Kavita Jain, Gauri Shukla, Priti Sharma, Rajeev Gupta, Manju Purohit
article en

Abstract

Glomangiopericytoma of the sinonasal type is a rare sinonasal soft tissue tumor of low malignant potential. Its nosologic nature was controversial after it was first reported by Stout and Murray in 1942, who termed it as sinonasal haemangiopericytoma. It behaves very indolently as compared to its soft tissue counterparts, and now its cell of origin is known to be a perivascular modified glomus-like cell with myoid features. Clinically, it has many mimics ranging from inflammatory nasal polyps to epithelial neoplasms and vascular tumors. Here, we report a case in a 52-year-old male patient who presented with epistaxis and sinonasal polypoid mass. CT/CECT showed a polypoid lesion involving the right nasal cavity between the right middle turbinate and bony nasal septum with the possibility of a small mucosal nasal polyp. Total resection was performed by endoscopic nasal route. On histopathology and immunohistochemical examination, it was diagnosed as sinonasal glomangiopericytoma (GPC). We discuss the histology features and differentials to help in the diagnosis of this rare nasal neoplasm that presents with common symptoms of epistaxis diagnosis.

Central India Journal of Medical ResearchVol. 4(01)
Government ENT Hospital (IN), Ruxmaniben Deepchand Gardi Medical College (IN)
Openalex Percentile: Top 87%
Soft tissue tumor case studies
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