Effects of Vitamin <scp>B12</scp> Deficiency on Hemogram Parameters and Its Relationship With Thyroid Hormones in Infancy
In conclusion, B12 deficiency during infancy can cause significant changes in hemogram parameters. During this period, when physiological anaemia is common, MCV may remain normal. Neutropenia and a lower Neu/Lym ratio appear to be the most striking hemogram parameters associated with vitamin B12 deficiency in infants undergoing routine check-ups. Decreased TSH levels may be related to B12 deficiency, and the NEU/LYM ratio could serve as a predictor of thyroid dysfunction. This study stands out as a large-scale study demonstrating the effects of B12 deficiency on haematological and thyroid parameters.
Authors
- Dilek Konuksever (ORCID: https://orcid.org/0000-0003-2334-9590)
- Sevinç Püren Yücel (ORCID: https://orcid.org/0000-0002-5768-3549)
- Büşra Demirci (ORCID: https://orcid.org/0009-0002-8014-4743)
- Gülşah Efeoğlu Gülsoy (ORCID: https://orcid.org/0000-0002-5273-9371)
Institutions
- Bilkent University (TR)
- Ankara Bilkent City Hospital (TR)
- Cukurova University (TR)
Publication Details
- Journal
- Journal of Paediatrics and Child Health
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1111/jpc.70065
- Citations
- 1
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 1.67