ClipKIT in the browser: fast online trimming of multiple sequence alignments for phylogenetics

Multiple sequence alignment trimming can help improve phylogenetic signal and reduce computational load. ClipKIT trims multiple sequence alignments by retaining phylogenetically informative sites and removing all others. Here, we present a web browser application for ClipKIT, which supports DNA, protein, and codon data types in FASTA format. The web browser application can process one or many multiple sequence alignment files, which users can subsequently download. Users can also view the trimmed multiple sequence alignment using a web-based multiple sequence alignment viewer. ClipKIT is available at https://clipkit.genomelybio.com, is free and open to all users, and there is no login requirement. ClipKIT in the browser aims to broaden the accessibility of web-based tools for phylogenetics research.

Authors

Institutions

Publication Details

Journal
Nucleic Acids Research
Published
2025-04-22
DOI
https://doi.org/10.1093/nar/gkaf325
Citations
1
Primary Topic
Genomics and Phylogenetic Studies
Type
article
Field-Weighted Citation Impact
0.81

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

ClipKIT in the browser: fast online trimming of multiple sequence alignments for phylogenetics

Thomas J. Buida, Jacob L. Steenwyk, Jeffrey T Loucks
1 citations
Nucleic Acids Research
Genomics and Phylogenetic Studies
0.81
article

ClipKIT in the browser: fast online trimming of multiple sequence alignments for phylogenetics

Thomas J. Buida, Jacob L. Steenwyk, Jeffrey T Loucks
article en
1 citations

Abstract

Multiple sequence alignment trimming can help improve phylogenetic signal and reduce computational load. ClipKIT trims multiple sequence alignments by retaining phylogenetically informative sites and removing all others. Here, we present a web browser application for ClipKIT, which supports DNA, protein, and codon data types in FASTA format. The web browser application can process one or many multiple sequence alignment files, which users can subsequently download. Users can also view the trimmed multiple sequence alignment using a web-based multiple sequence alignment viewer. ClipKIT is available at https://clipkit.genomelybio.com, is free and open to all users, and there is no login requirement. ClipKIT in the browser aims to broaden the accessibility of web-based tools for phylogenetics research.

Nucleic Acids ResearchVol. 53(W1)
Howard Hughes Medical Institute (US), Nashville Oncology Associates (US), University of California, Berkeley (US)
Life Sciences Research Foundation
Openalex Percentile: Top 29%
Genomics and Phylogenetic Studies
0.81
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.