Wernicke’s encephalopathy complicated by perforated gastric ulcer: A case report

Wernicke’s encephalopathy (WE) is a neurological disorder that arises from thiamine (vitamin B1) deficiency, often seen in patients with chronic alcoholism, malnutrition, or other conditions affecting thiamine absorption. This case report discusses a 50-year-old woman with a history of hypertension, chronic smoking, alcohol consumption, and a previous hemorrhagic gastric ulcer who developed WE complicated by a perforated gastric ulcer. The patient’s condition highlights the importance of considering WE in the differential diagnosis of patients presenting with gastrointestinal pathology and neurological symptoms, especially when there are risk factors for thiamine deficiency.

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Publication Details

Journal
World Journal of Advanced Research and Reviews
Published
2025-04-22
DOI
https://doi.org/10.30574/wjarr.2025.26.1.1337
Primary Topic
Alcoholism and Thiamine Deficiency
Type
article
Field-Weighted Citation Impact
0.00
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Wernicke’s encephalopathy complicated by perforated gastric ulcer: A case report

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World Journal of Advanced Research and Reviews
Alcoholism and Thiamine Deficiency
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Wernicke’s encephalopathy complicated by perforated gastric ulcer: A case report

Said Ait Laalim, Anass Ahallat, Anass Barchid, Omar Bennour, Youness Aggouri, Houssam boukabouss
article en

Abstract

Wernicke’s encephalopathy (WE) is a neurological disorder that arises from thiamine (vitamin B1) deficiency, often seen in patients with chronic alcoholism, malnutrition, or other conditions affecting thiamine absorption. This case report discusses a 50-year-old woman with a history of hypertension, chronic smoking, alcohol consumption, and a previous hemorrhagic gastric ulcer who developed WE complicated by a perforated gastric ulcer. The patient’s condition highlights the importance of considering WE in the differential diagnosis of patients presenting with gastrointestinal pathology and neurological symptoms, especially when there are risk factors for thiamine deficiency.

World Journal of Advanced Research and ReviewsVol. 26(1)
Openalex Percentile: Top 86%
Alcoholism and Thiamine Deficiency
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