Association of Amygdala and Hippocampus Volumes With Histopathological Diagnosis in Patients With Temporal Lobe Epilepsy

Mesial temporal lobe epilepsy (TLE) can present with different pathologic patterns, including hippocampal sclerosis (HS) and hippocampal gliosis (HG). However, the volumetric relationships between ipsilateral and contralateral amygdala and hippocampus in unilateral TLE remain poorly understood. This study aimed to identify systematic volumetric differences between ipsilateral and contralateral amygdala and hippocampus using 3T MRI volumetry.

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Publication Details

Journal
Neurology Open Access
Published
2025-04-22
DOI
https://doi.org/10.1212/wn9.0000000000000010
Citations
2
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
2.94
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article

Association of Amygdala and Hippocampus Volumes With Histopathological Diagnosis in Patients With Temporal Lobe Epilepsy

Horst Urbach, Anke M. Staack, Christian F. Scheiwe, Kai Schumacher et al.
2 citations
Neurology Open Access
Epilepsy research and treatment
2.94
article

Association of Amygdala and Hippocampus Volumes With Histopathological Diagnosis in Patients With Temporal Lobe Epilepsy

Horst Urbach, Anke M. Staack, Christian F. Scheiwe, Kai Schumacher, Theo Demerath, Bernhard J. Steinhoff, Marcel Heers, Peter Christoph Reinacher, Soroush Doostkam, Christoph P. Kaller, Andreas Schulze‐Bonhage, Dirk Matthias Altenmüller, Yaron Rohrer, Cem Yildirim
article en
2 citations

Abstract

Mesial temporal lobe epilepsy (TLE) can present with different pathologic patterns, including hippocampal sclerosis (HS) and hippocampal gliosis (HG). However, the volumetric relationships between ipsilateral and contralateral amygdala and hippocampus in unilateral TLE remain poorly understood. This study aimed to identify systematic volumetric differences between ipsilateral and contralateral amygdala and hippocampus using 3T MRI volumetry.

Neurology Open AccessVol. 1(2)
University of Freiburg (DE), University Medical Center Freiburg (DE), Diakonie Kork (DE)
Good health and well-being
Openalex Percentile: Top 10%
Epilepsy research and treatment
2.94
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Association of Amygdala and Hippocampus Volumes With Histopathological Diagnosis in Patients With Temporal Lobe Epilepsy — Horst Urbach, Anke M. Staack, et al. · Neurology Open Access (2025) | TGRS Research Map | TGRS