Identification of novel biomarkers and prognostic model for neuroblastoma using Mendelian randomization and transcriptomic analysis
Our findings provide new insights into the molecular basis of NB, identifying four novel biomarkers and developing a risk scoring model based on four co-expressed genes. This model has the potential to become an effective tool for predicting prognosis and guiding treatment in NB patients.
Authors
- Jian Cheng (ORCID: https://orcid.org/0000-0001-7846-2254)
- Xiaohan Qin (ORCID: https://orcid.org/0000-0001-6895-4191)
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0003-4987-3892)
- Nan Zhang (ORCID: https://orcid.org/0000-0002-5877-1786)
- Da Zhang (ORCID: https://orcid.org/0000-0002-1947-1158)
- Xiaoran Du
- Jingyue Wang (ORCID: https://orcid.org/0000-0001-8796-9612)
- Xing Zhou (ORCID: https://orcid.org/0000-0002-9251-7714)
- Yongcheng Fu
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1007/s12672-025-02414-5
- Citations
- 1
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Key Scientific Research Project of Colleges and Universities in Henan Province