Index cases of intracranial aneurysms in autosomal dominant polycystic kidney disease: longitudinal experience from a single renal transplantation centre

Early detection of ICAs and pre-aneurysmal changes should be prioritized in ADPKD. Although limited by the small study cohort, our findings are consistent with previous literature suggesting ICA ruptures occur earlier in ADPKD and in smaller aneurysms. Further investigation is required into how these ICAs behave. Nonetheless, it is vital that centres coordinate a multidisciplinary, patient-centred approach to ICA screening, surveillance, and management for ADPKD patients.