The Burden of Rheumatic Chorea in the Modern Era: A Case Series From a Tertiary Health Care Center in South India

Rheumatic chorea is the most common acquired etiology of childhood chorea, especially in low-income countries, and it can be the only manifestation of rheumatic fever, making it ample for diagnosis.It often occurs in children of 5 and 14 years and can rarely be the initial manifestation(1,2).Key contributors to the prevalence include factors such as poverty, overcrowding, and limited access to quality healthcare services(3).The incidence and prevalence of rheumatic chorea have changed over time, majorly due to improvements in patient care and widespread prophylactic antibiotic use (4).Though it has become uncommon in developed countries, it persists in significant numbers in developing nations.Despite decades of research, several knowledge gaps remain regarding the pathophysiology, diagnosis, treatment, and long-term outcomes of rheumatic chorea.Addressing these gaps, future research could lead to better prevention strategies, more targeted treatments, and improved outcomes of affected individuals.This retrospective study will bring a detailed demographic, clinical,