Niclosamide extends health span and reduces frailty by ameliorating mTORC1 hyperactivation in aging models
Collectively, these findings suggest that NIC is a promising novel candidate for the prevention of frailty.
Authors
- Chang Hwa Jung (ORCID: https://orcid.org/0000-0002-1076-750X)
- Jiyun Ahn (ORCID: https://orcid.org/0000-0002-5930-2957)
- Tae‐Il Jeon (ORCID: https://orcid.org/0000-0003-0655-8614)
- Pyeong Geun Choi (ORCID: https://orcid.org/0000-0001-8973-1050)
- Jeong‐Hoon Hahm (ORCID: https://orcid.org/0000-0003-2446-2974)
- Yang Hoon Huh (ORCID: https://orcid.org/0000-0003-3157-304X)
- Hyo‐Deok Seo (ORCID: https://orcid.org/0000-0002-7294-4348)
- So‐Hyun Park (ORCID: https://orcid.org/0000-0002-9071-9435)
- Hee Soo Kim (ORCID: https://orcid.org/0009-0008-6697-2271)
Institutions
- Chonnam National University (KR)
- Korea Food Research Institute (KR)
- Korea Basic Science Institute (KR)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.jare.2025.04.027
- Citations
- 4
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 3.81
Funders
- Korea Food Research Institute