A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis

This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia, offers a novel approach to managing complex cases involving both rare disorders.

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Publication Details

Journal
Journal of Allergy and Clinical Immunology Global
Published
2025-04-22
DOI
https://doi.org/10.1016/j.jacig.2025.100481
Primary Topic
Eosinophilic Disorders and Syndromes
Type
article
Field-Weighted Citation Impact
0.00
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article

A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis

Sara Iqbal, John D. Baxter, Karla E. Adams
Journal of Allergy and Clinical Immunology Global
Eosinophilic Disorders and Syndromes
article

A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis

Sara Iqbal, John D. Baxter, Karla E. Adams
article en

Abstract

This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia, offers a novel approach to managing complex cases involving both rare disorders.

Journal of Allergy and Clinical Immunology GlobalVol. 4(3)
Wilford Hall Ambulatory Surgical Center (US), Malcolm Grow Medical Clinic (US), United States Air Force (US), Joint Base San Antonio (US)
Zero hunger
Openalex Percentile: Top 87%
Eosinophilic Disorders and Syndromes
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