Lacking ASIC1a in ASIC4-positive amygdala/bed nucleus of the stria terminalis (BNST) neurons reduces anxiety and innate fear in mice
Together, these data suggest that ASIC4 plays an important role in fear and anxiety-related behaviors in mice by modulating ASIC1a activity in the amygdala and BNST.
Authors
- Cheng‐Chang Lien (ORCID: https://orcid.org/0000-0002-6692-9942)
- John N. Wood (ORCID: https://orcid.org/0000-0002-9166-8158)
- Ya‐Chih Chien
- Chih‐Cheng Chen (ORCID: https://orcid.org/0000-0003-4768-5660)
- Shing-Hong Lin (ORCID: https://orcid.org/0000-0002-8012-6935)
Institutions
- National Yang Ming Chiao Tung University (TW)
- Genomics Research Center, Academia Sinica (TW)
- Institute of Biomedical Sciences, Academia Sinica (TW)
- Institute of Molecular Biology, Academia Sinica (TW)
- University College London (GB)
- Academia Sinica (TW)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1186/s12929-025-01138-6
- Citations
- 2
- Primary Topic
- Ion Transport and Channel Regulation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Academia Sinica