Dynamic brain glymphatic changes and cognitive function in COVID-19 recovered patients: a DTI-ALPS prospective cohort study
This study demonstrates dynamic changes in brain glymphatic function in COVID-19 recovered patients, with a peak in activity at 3 months post-recovery. These changes are associated with cognitive function and mental fatigue, suggesting potential targets for addressing neurological symptoms of long COVID. The non-invasive DTI-ALPS technique proves to be a valuable tool for assessing brain glymphatic function in this population.
Authors
- Yangyang Shi (ORCID: https://orcid.org/0000-0003-2187-2994)
- Jindong Xie (ORCID: https://orcid.org/0000-0002-2482-7358)
- Juan Fu (ORCID: https://orcid.org/0009-0003-5800-3546)
- Bin Guo (ORCID: https://orcid.org/0000-0001-5950-8974)
- Hua Li (ORCID: https://orcid.org/0000-0002-6816-0786)
- Weiwei Fang (ORCID: https://orcid.org/0000-0002-2701-5216)
- Chengcheng He (ORCID: https://orcid.org/0000-0002-5855-9611)
- Shaoyu Wang (ORCID: https://orcid.org/0000-0003-3676-0004)
- Zhimin Zhu
- Anan Li (ORCID: https://orcid.org/0000-0003-0037-5980)
- Xuan Niu
- Wenrui Bao
- Wenjuan Xie (ORCID: https://orcid.org/0000-0001-9368-8411)
- Hao Liu (ORCID: https://orcid.org/0000-0002-2378-195X)
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Yulin University (CN)
- Yulin Orthopedics Hospital of Chinese and Western Medicine (CN)
- Siemens (China) (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Psychology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3389/fpsyg.2025.1465660
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.91