Avoiding Long Antibiotic Regimen For Diabetic Foot Osteomyelitis Through Application Of Bioresorbable Calcium Sulfate Beads Impregnated With Tobramycin And Vancomycin: A Case Presentation

Diabetic foot osteomyelitis, given the multiple comorbidities of the patient, antibiotic resistance and potential for recurrence, poses a significant challenge for the treating clinicians and patients alike. Combinations of intravenous (IV) and oral (PO) antibiotic therapy, with or without surgical debridement, are standard treatment methods. The authors present a case of osteomyelitis cured through the application of bioresorbable calcium sulfate beads impregnated with tobramycin and vancomycin as an adjunct to surgical bone debridement. Simple offloading using isolation in felt was employed. This approach led to the complete healing of the infection and ulcer without recurrence, thereby avoiding hospitalization and amputation.