Evaluation of the Potency of the First Commercial Vaccine for Clostridioides difficile Infection in Piglets and Comparison with the Humoral Response in Rabbits
The tested vaccine can induce a humoral immune response against <i>C. difficile</i> A/B toxins in sows and these antibodies are passively transferred to neonatal piglets through colostrum. Also, the vaccination of rabbits might be a useful alternative for evaluating the potency of vaccines against <i>C. difficile</i>.
Authors
- Victor Santos do Amarante (ORCID: https://orcid.org/0000-0001-9912-2566)
- João Victor Ferreira Campos (ORCID: https://orcid.org/0000-0003-0902-0000)
- Rodrigo Otávio Silveira Silva (ORCID: https://orcid.org/0000-0003-0074-2488)
- Thayanne Gabryelle Viana de Souza (ORCID: https://orcid.org/0000-0002-7611-7403)
- Yasmin Gonçalves de Castro (ORCID: https://orcid.org/0000-0002-4672-9812)
- Kelly Mara Gomes Godoy
Institutions
- Universidade Federal de Minas Gerais (BR)
Publication Details
- Journal
- Vaccines
- Published
- 2025-04-22
- DOI
- https://doi.org/10.3390/vaccines13050438
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico