Effect of drinking, smoking, and smartphone overdependence on drug addiction among Korean adolescents

Alcohol consumption, smoking, and smartphone overdependence significantly elevate the risk of drug addiction among adolescents, with interaction effects exacerbating this vulnerability. Early initiation of drinking and smoking is particularly associated with a heightened addiction risk. A comprehensive understanding of these interaction effects and dose-response relationships is imperative for the formulation of evidence-based, targeted prevention strategies to mitigate adolescent substance use and addiction.