A pilot study on the programming protocol of vagus nerve stimulation in children with drug‐resistant epilepsy: High pulse amplitude or high duty cycle
This study compared the anti-seizure efficacy of two different vagus nerve stimulation (VNS) treatments. We found that the overall efficacy of the two treatments was similar. The high pulse amplitude mode may be more effective for focal seizures, whereas the high duty cycle mode may be more effective for epileptic spasms. Patients aged <6 years with drug-resistant epilepsy (DRE) and VNS treatment may require a higher pulse amplitude to achieve better efficacy.
Authors
- Qingzhu Liu (ORCID: https://orcid.org/0000-0002-9695-2246)
- Taoyun Ji (ORCID: https://orcid.org/0000-0003-0098-3257)
- Lixin Cai (ORCID: https://orcid.org/0000-0001-8231-6428)
- Ye Wu (ORCID: https://orcid.org/0000-0001-9644-9520)
- Han Xie (ORCID: https://orcid.org/0000-0002-5583-0576)
- Yuying Pan
- Kai Zhang (ORCID: https://orcid.org/0000-0002-9609-7788)
- Jianguo Zhang (ORCID: https://orcid.org/0000-0002-0009-0574)
- Jiayi Ma (ORCID: https://orcid.org/0000-0002-9232-1770)
Institutions
- Capital Medical University (CN)
- Peking University (CN)
- Beijing Tian Tan Hospital (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1002/epi4.70043
- Citations
- 1
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84