Enhanced Therapeutic Effect of IL-10-ADSCs on Rabbit Autoimmune Dacryoadenitis By Suppressing T Follicular Helper Cell Responses Via miR-142-5p/RC3H1 Axis
IL-10-ADSCs ameliorate autoimmune dacryoadenitis by suppressing Tfh cell responses via suppressing the miR-142-5p/RC3H1 axis. The enhanced therapeutic effects of IL-10-ADSCs could be of significant value in improving the effectiveness of stem cell therapy in autoimmune dry eye.
Authors
- Hong Nian
- Deming Sun (ORCID: https://orcid.org/0000-0003-4851-0416)
- Ruihua Wei (ORCID: https://orcid.org/0000-0002-9708-0355)
- Lu Zhao (ORCID: https://orcid.org/0000-0002-8055-5211)
- Yankai Wei (ORCID: https://orcid.org/0000-0003-4906-258X)
- Na Li (ORCID: https://orcid.org/0000-0002-4112-0944)
- Jiachen Zhang (ORCID: https://orcid.org/0000-0001-9546-9159)
- Min Gao (ORCID: https://orcid.org/0000-0002-6888-2965)
- Bei Du
- Xinrui Shi
- Xuejia Li
Institutions
- University of California, Los Angeles (US)
- Doheny Eye Institute (US)
- ORCID (US)
- Tianjin Medical University Eye Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1167/iovs.66.4.66
- Citations
- 2
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 1.59