Iris Pigmented Lesions: Unraveling the Genetic Basis of Iris Freckles and Nevi
The genetic basis of iris freckles and nevi reveals associations with well-known pigmentation genes (particularly IRF4), as well as eye color, sex, and age. These findings contribute to our understanding of iris pigmented benign lesions and their potential implications in conditions such as uveal melanoma, age-related macular degeneration, or solar damage.
Authors
- Conrado Martínez‐Cadenas (ORCID: https://orcid.org/0000-0002-5252-563X)
- Alfonso Anton (ORCID: https://orcid.org/0000-0001-6955-2055)
- Alba Loras (ORCID: https://orcid.org/0000-0003-1426-1765)
- Julia Boldu-Roig
- Elena Sorli-Clemente
- Aida Kuljuh-Causevic
Institutions
- Universitat Jaume I (ES)
- Institut Català de Retina (ES)
- Hospital General Universitari de Castelló (ES)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1167/iovs.66.4.62
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00