Therapeutic potential of quercitrin in intervertebral disc degeneration: Targeting pyroptosis and inflammation
QUE plays an important role in alleviating pyroptosis and inflammation within NPCs, thereby slowing the progression of IDD. Therefore, QUE might emerge as a promising therapeutic candidate for IDD, holding the potential for clinical application in the future.
Authors
- Zhangfu Wang (ORCID: https://orcid.org/0000-0001-6592-5213)
- Zhenghua Hong (ORCID: https://orcid.org/0000-0002-1856-888X)
- Qing Pan (ORCID: https://orcid.org/0000-0002-4372-5349)
- Yiyu Chen (ORCID: https://orcid.org/0000-0002-8671-1406)
- Fang Tang (ORCID: https://orcid.org/0000-0001-5070-2922)
- Yuxuan Bao (ORCID: https://orcid.org/0000-0001-5660-6077)
- Zhiyu Fang
- Min Yu (ORCID: https://orcid.org/0000-0003-3309-4261)
- Yunfei Li (ORCID: https://orcid.org/0000-0002-5676-403X)
- Xinyu Wu (ORCID: https://orcid.org/0000-0002-9094-9951)
- Chao Yao (ORCID: https://orcid.org/0000-0001-5483-3225)
- Chao Jiang (ORCID: https://orcid.org/0000-0002-8801-8576)
- Yuhang Gong
Institutions
- Wenzhou Medical University (CN)
- Zhejiang Taizhou Hospital (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.intimp.2025.114680
- Citations
- 5
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 7.36
Funders
- Science and Technology Plan Project of Taizhou
- Natural Science Foundation of Zhejiang Province
- Basic Public Welfare Research Program of Zhejiang Province