Identification of key biomarker genes in liver hepatocellular carcinoma and kidney renal clear cell carcinoma progression: A shared high-throughput screening and molecular docking method with potentials for targeted therapeutic interventions
Our study emphasizes TOP2A's prognostic significance in KIRC and LIHC and recognizes Andrographis paniculata compound as potential therapeutics, offering prospective for enhanced treatment and patient outcomes in these cancers.
Authors
- Maisha Tasneem (ORCID: https://orcid.org/0000-0002-9043-4405)
- Shipan Das Gupta (ORCID: https://orcid.org/0000-0002-3236-519X)
- Jannatul Ferdoush
- Rajib Kumar Dey (ORCID: https://orcid.org/0009-0000-3728-4746)
- Md Jubair Ahmed Jony
- Maya Minkara
Institutions
- University of Tennessee at Chattanooga (US)
- Chittagong Medical College (BD)
- Noakhali Science and Technology University (BD)
Publication Details
- Journal
- Journal of Genetic Engineering and Biotechnology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.jgeb.2025.100497
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- University of Tennessee at Chattanooga