The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model
The hydrogel effectively prolonged MMC presence in plasma, suggesting extended intraperitoneal residence time and supporting previous findings of therapeutic effectiveness in a PM rat model.
Authors
- Wouter Marchal (ORCID: https://orcid.org/0000-0001-5105-8112)
- Marion J. Gijbels (ORCID: https://orcid.org/0000-0002-4906-0384)
- Patricia Y. W. Dankers (ORCID: https://orcid.org/0000-0002-8997-181X)
- Kurt Van der Speeten (ORCID: https://orcid.org/0000-0001-8899-7834)
- Kaatje Lenaerts (ORCID: https://orcid.org/0000-0002-9858-0538)
- Anne G. W. E. Wintjens (ORCID: https://orcid.org/0000-0001-8120-4248)
- Nicole D. Bouvy (ORCID: https://orcid.org/0000-0003-4070-8559)
- Ignace H. J. T. de Hingh (ORCID: https://orcid.org/0000-0003-3491-4268)
- Peter-Paul K. H. Fransen (ORCID: https://orcid.org/0000-0003-3831-4649)
- Geert C. van Almen
- Hong Liu (ORCID: https://orcid.org/0000-0003-3611-7131)
- Ben Janssen
Institutions
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Catharina Ziekenhuis (NL)
- Maastricht University (NL)
- Transnational University Limburg (BE)
- Ziekenhuis Oost-Limburg (BE)
- Eindhoven University of Technology (NL)
- Hasselt University (BE)
Publication Details
- Journal
- Journal of Controlled Release
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.jconrel.2025.113763
- Citations
- 1
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Universiteit Maastricht