Monotherapy Blood Pressure Response and Control Rates in Treatment-Naïve Patients with Arterial Hypertension: A Randomized Comparison of Four Different Antihypertensive Drug Classes
Initial antihypertensive monotherapy failed in most patients (73% uncontrolled, 21%/18% reached optimal treatment goal at TP1) even in low-risk patients, with efficacy varying by drug class (inhibitors of the renin-angiotensin-aldosterone system best, HCT least). These findings support guideline-recommended combination therapy.
Authors
- Thenral Socrates (ORCID: https://orcid.org/0000-0001-9619-5460)
- Michael Mayr (ORCID: https://orcid.org/0000-0002-1962-8186)
- Fu‐Tsai Kung (ORCID: https://orcid.org/0000-0003-0565-6976)
- Annina Salome Vischer (ORCID: https://orcid.org/0000-0001-5188-1723)
- Vera van der Velpen (ORCID: https://orcid.org/0000-0002-6502-7197)
- Manuel Haschke (ORCID: https://orcid.org/0000-0003-1846-8640)
- Thilo Burkard (ORCID: https://orcid.org/0000-0001-6373-9820)
- Maria Bertsch
Institutions
- University of Basel (CH)
- University Hospital of Bern (CH)
- University Hospital of Basel (CH)
- Kantonsspital Baselland Standort Bruderholz (CH)
Publication Details
- Journal
- Kidney & Blood Pressure Research
- Published
- 2025-04-21
- DOI
- https://doi.org/10.1159/000545908
- Citations
- 1
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39