Prognostic prediction model for Chinese uveal melanoma patients based on matrix metalloproteinase-2 and -28 expression levels in the tumor

Based on MMP-2 and MMP-28 expression levels, our prediction model demonstrates accurate long-term prognosis prediction for UM patients. The aggregation of TAMs and regulatory T cells in the TME of UM may be associated with an unfavorable prognosis.

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Publication Details

Journal
International Journal of Ophthalmology
Published
2025-04-23
DOI
https://doi.org/10.18240/ijo.2025.05.02
Citations
1
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
1.71

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article

Prognostic prediction model for Chinese uveal melanoma patients based on matrix metalloproteinase-2 and -28 expression levels in the tumor

Yuning Chen, Jingting Luo, Hanqing Zhao, Li Yang et al.
1 citations
International Journal of Ophthalmology
Ocular Oncology and Treatments
1.71
article

Prognostic prediction model for Chinese uveal melanoma patients based on matrix metalloproteinase-2 and -28 expression levels in the tumor

Yuning Chen, Jingting Luo, Hanqing Zhao, Li Yang, Wenbin Wei, Qiong Yang
article en
1 citations

Abstract

Based on MMP-2 and MMP-28 expression levels, our prediction model demonstrates accurate long-term prognosis prediction for UM patients. The aggregation of TAMs and regulatory T cells in the TME of UM may be associated with an unfavorable prognosis.

International Journal of OphthalmologyVol. 18(5)
Beijing Tongren Hospital (CN), Capital Medical University (CN)
National Natural Science Foundation of China, Sanming Project of Medicine in Shenzhen
Openalex Percentile: Top 19%
Ocular Oncology and Treatments
1.71
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Prognostic prediction model for Chinese uveal melanoma patients based on matrix metalloproteinase-2 and -28 expression levels in the tumor — Yuning Chen, Jingting Luo, et al. · International Journal of Ophthalmology (2025) | TGRS Research Map | TGRS