Collagen (rs3134646) and ARHGAP15 (rs4662344) genetic variants may predispose to colonic diverticulosis
The allele C of COL3A1 (rs3134646) and allele T of the ARHGAP15 (rs4662344) may predispose to colonic diverticulosis. When viewed in the context of previous studies, these findings suggest that the development of colonic diverticula may be influenced by the involvement and degradation of the extracellular matrix.
Authors
- Piotr Nehring (ORCID: https://orcid.org/0000-0003-3118-7843)
- Grzegorz Placha (ORCID: https://orcid.org/0000-0002-6106-2454)
- Adam M. Przybyłkowski (ORCID: https://orcid.org/0000-0002-5851-2856)
Institutions
- Medical University of Warsaw (PL)
Publication Details
- Journal
- Advances in Medical Sciences
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.advms.2025.04.001
- Citations
- 1
- Primary Topic
- Diverticular Disease and Complications
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Warszawski Uniwersytet Medyczny