3'-epi-12β-hydroxyfroside induces autophagic degradation of ABCG2 to overcome drug resistance in lung cancer cells
These findings highlight the potential of HyFS in overcoming drug resistance through autophagy-dependent degradation of ABCG2, suggesting its promise as a therapeutic approach against ABCG2-mediated drug resistance in lung cancer cells.
Authors
- Feng‐Ying Huang (ORCID: https://orcid.org/0000-0001-9677-6855)
- Guang‐Hong Tan (ORCID: https://orcid.org/0000-0002-6406-0331)
- Wenhui Xie
- Shu-Zhen Dai
- Minghui Chen (ORCID: https://orcid.org/0009-0001-2086-2914)
- Ri-Hong Wu (ORCID: https://orcid.org/0009-0005-4094-4086)
Institutions
- Hainan Medical University (CN)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.biopha.2025.118085
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hainan Province