The role of m6A in plant development, stress response, and agricultural practices
N6-methyladenosine (m 6 A) modification, the most abundant internal modification in messenger RNA (mRNA) and long non-coding RNA (lncRNA), has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes. While the importance of m 6 A modification in various biological processes has been recognized, a comprehensive understanding of its diverse roles in plant biology and agricultural applications remains fragmented. This review analyzes recent advances in m 6 A modification's biological functions in plants. m 6 A modification plays crucial roles in multiple aspects of plant life, including seed germination, organ development, and reproductive structure formation. Furthermore, m 6 A has been found to significantly influence plant responses to environmental stresses, including salt, drought, temperature, and heavy metal exposure. We also uncover m 6 A involvement in important agricultural traits. This review provides insights into the mechanistic understanding of m 6 A modification in plants and highlights its applications in agricultural improvement, offering a foundation for future research in crop enhancement and stress resistance.
Authors
- Shaoxia Li (ORCID: https://orcid.org/0000-0002-2430-3992)
- Yushi Lu (ORCID: https://orcid.org/0000-0002-0976-4213)
- Changxia Li (ORCID: https://orcid.org/0000-0001-8570-4653)
- Wenjin Yu
- Jun Su
- Jin Qi (ORCID: https://orcid.org/0000-0003-2321-8953)
Institutions
- Guangxi University (CN)
Publication Details
- Journal
- Horticultural Plant Journal
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.hpj.2025.02.006
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61