The role of m6A in plant development, stress response, and agricultural practices

N6-methyladenosine (m 6 A) modification, the most abundant internal modification in messenger RNA (mRNA) and long non-coding RNA (lncRNA), has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes. While the importance of m 6 A modification in various biological processes has been recognized, a comprehensive understanding of its diverse roles in plant biology and agricultural applications remains fragmented. This review analyzes recent advances in m 6 A modification's biological functions in plants. m 6 A modification plays crucial roles in multiple aspects of plant life, including seed germination, organ development, and reproductive structure formation. Furthermore, m 6 A has been found to significantly influence plant responses to environmental stresses, including salt, drought, temperature, and heavy metal exposure. We also uncover m 6 A involvement in important agricultural traits. This review provides insights into the mechanistic understanding of m 6 A modification in plants and highlights its applications in agricultural improvement, offering a foundation for future research in crop enhancement and stress resistance.

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Publication Details

Journal
Horticultural Plant Journal
Published
2025-04-22
DOI
https://doi.org/10.1016/j.hpj.2025.02.006
Citations
2
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
1.61
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article

The role of m6A in plant development, stress response, and agricultural practices

Shaoxia Li, Yushi Lu, Changxia Li, Wenjin Yu et al.
2 citations
Horticultural Plant Journal
RNA modifications and cancer
1.61
article

The role of m6A in plant development, stress response, and agricultural practices

Shaoxia Li, Yushi Lu, Changxia Li, Wenjin Yu, Jun Su, Jin Qi
article en
2 citations

Abstract

N6-methyladenosine (m 6 A) modification, the most abundant internal modification in messenger RNA (mRNA) and long non-coding RNA (lncRNA), has emerged as a critical epitranscriptomic regulatory mechanism in eukaryotes. While the importance of m 6 A modification in various biological processes has been recognized, a comprehensive understanding of its diverse roles in plant biology and agricultural applications remains fragmented. This review analyzes recent advances in m 6 A modification's biological functions in plants. m 6 A modification plays crucial roles in multiple aspects of plant life, including seed germination, organ development, and reproductive structure formation. Furthermore, m 6 A has been found to significantly influence plant responses to environmental stresses, including salt, drought, temperature, and heavy metal exposure. We also uncover m 6 A involvement in important agricultural traits. This review provides insights into the mechanistic understanding of m 6 A modification in plants and highlights its applications in agricultural improvement, offering a foundation for future research in crop enhancement and stress resistance.

Horticultural Plant JournalVol. 12(1)
Guangxi University (CN)
Zero hunger
Openalex Percentile: Top 18%
RNA modifications and cancer
1.61
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