A novel TGR5 agonist Sauchinone ameliorates IMQ induced murine psoriasis by regulating macrophage polarization
Our work identified Sauchinone as a novel TGR5 agonist that could ameliorate IMQ induced murine psoriasis by regulating macrophage polarization.
Authors
- Qin‐Shi Zhao
- Yipei Gu
- Ke Zhu (ORCID: https://orcid.org/0000-0002-0157-8969)
- Suling Huang (ORCID: https://orcid.org/0000-0003-2338-8004)
- Jing Ren (ORCID: https://orcid.org/0000-0003-4488-9297)
- Lixin Chen (ORCID: https://orcid.org/0000-0002-5163-5116)
- Lu Cao (ORCID: https://orcid.org/0000-0002-5159-7615)
- Haoyu Wang (ORCID: https://orcid.org/0000-0001-6647-598X)
- Ling Qi (ORCID: https://orcid.org/0000-0001-8229-0184)
- Wei Tang (ORCID: https://orcid.org/0000-0001-8811-4798)
- Rong Zhou (ORCID: https://orcid.org/0000-0002-0966-3711)
- Li‐Yan Peng (ORCID: https://orcid.org/0000-0002-8351-2882)
- Ying Leng
- Chunlan Feng
Institutions
- Nanjing University of Chinese Medicine (CN)
- Kunming Institute of Botany (CN)
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Materia Medica (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.jare.2025.04.034
- Citations
- 2
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality