Disulfidptosis, a novel regulated cell death to predict survival and therapeutic response in kidney renal clear cell carcinoma
This study established a robust DAG-based risk model for KIRC, highlighting its significant correlation with the immune landscape and therapeutic responses. Novel disulfidptosis-related biomarkers revealed distinct immune profiles, drug sensitivities, and immunotherapy potentials among KIRC patients.
Authors
- De Zeng (ORCID: https://orcid.org/0000-0002-9141-5505)
- Leonardo Antonio Sechi (ORCID: https://orcid.org/0000-0003-0566-2049)
- Minna Chen
- Maria R. De Miglio (ORCID: https://orcid.org/0000-0002-9393-3234)
- Danxia Lin
- Jiaxin Shen (ORCID: https://orcid.org/0000-0003-0146-8863)
- Wen-Jia Chen (ORCID: https://orcid.org/0009-0007-6049-6529)
- Hui Lin (ORCID: https://orcid.org/0000-0002-3499-5806)
Institutions
- University of Sassari (IT)
- Shantou University (CN)
- Cancer Hospital of Shantou University Medical College (CN)
- Azienda Ospedaliero Universitaria di Sassari (IT)
- First Affiliated Hospital of Shantou University Medical College (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1007/s12672-025-01994-6
- Citations
- 1
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52