Immunophenotyping of bronchoalveolar lavage and functional impairment in post-COVID syndrome

A notable percentage of patients with post-COVID syndrome with persistent HRCT changes showed T‑helper lymphocytic inflammation in the lungs. The degree of alveolar lymphocytosis was associated with lung function impairment. This could suggest that a prolonged inflammatory response in the alveolar compartment contributes to the pathogenesis of post-COVID syndrome.

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Publication Details

Journal
Wiener klinische Wochenschrift
Published
2025-04-22
DOI
https://doi.org/10.1007/s00508-025-02531-9
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
0.00

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Immunophenotyping of bronchoalveolar lavage and functional impairment in post-COVID syndrome

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Immunophenotyping of bronchoalveolar lavage and functional impairment in post-COVID syndrome

Jonas Brugger, Andreas Zech, Daniela Gompelmann, Helmut Prosch, Dominik Bernitzky, Marco Idzko, Maximilian Robert Gysan, Antje Lehmann
article en

Abstract

A notable percentage of patients with post-COVID syndrome with persistent HRCT changes showed T‑helper lymphocytic inflammation in the lungs. The degree of alveolar lymphocytosis was associated with lung function impairment. This could suggest that a prolonged inflammatory response in the alveolar compartment contributes to the pathogenesis of post-COVID syndrome.

Wiener klinische WochenschriftVol. 137(21-22)
Medical University of Vienna (AT)
Medizinische Universität Wien
Good health and well-being
Openalex Percentile: Top 86%
Long-Term Effects of COVID-19
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