Quantification of baseline amyloid PET in individuals with subjective cognitive decline can identify risk of amyloid accumulation and cognitive worsening: the FACEHBI study
Baseline amyloid levels differentiate individuals who accumulate amyloid over time and that are at risk for cognitive decline, including those at sub-threshold levels of Aβ. This can be valuable to identify pre-clinical AD in a SCD population.
Authors
- Norman Koglin (ORCID: https://orcid.org/0000-0001-7583-8201)
- Marta Marquié (ORCID: https://orcid.org/0000-0002-0660-0950)
- Agustı́n Ruiz (ORCID: https://orcid.org/0000-0003-2633-2495)
- Andrew Stephens (ORCID: https://orcid.org/0000-0001-5052-6586)
- Santiago Bullich (ORCID: https://orcid.org/0000-0001-5669-269X)
- Merçé Boada (ORCID: https://orcid.org/0000-0003-2617-3009)
- Montserrat Alegret (ORCID: https://orcid.org/0000-0002-8164-9500)
- Ángela Sanabria (ORCID: https://orcid.org/0000-0002-7501-9895)
- Guilherme Domingues Kolinger (ORCID: https://orcid.org/0000-0001-9505-4869)
- Juan Pablo Tartari (ORCID: https://orcid.org/0000-0002-7548-2687)
- Núria Roé-Vellvé (ORCID: https://orcid.org/0000-0001-5583-8837)
- Óscar Sotolongo‐Grau (ORCID: https://orcid.org/0000-0002-9679-0670)
- Lluís Tárraga (ORCID: https://orcid.org/0000-0002-8423-946X)
- Esther Pérez-Martínez
- Miren Jone Gurruchaga
Institutions
- The University of Texas at San Antonio Health Science Center (US)
- Instituto de Salud Carlos III (ES)
- Universitat Internacional de Catalunya (ES)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
- Centro de Investigación Biomédica en Red (ES)
- Life University (US)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1007/s00259-025-07270-7
- Citations
- 2
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- European Commission
- Innovative Medicines Initiative
- Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas
- HORIZON EUROPE Marie Sklodowska-Curie Actions