Hypo-Fractionated Radiotherapy to the Cavity for Resected Brain Metastases: A UK Series

In this multicentre series of postoperative hypo-fractionated radiotherapy to the surgical cavity following resection of a brain metastasis, we demonstrated good rates of local control, with low risk of LMD and RN. Therefore, this radiotherapy regimen is a reasonable alternative to cavity SRS in patients with large cavity volumes or complete gross total resection within the UK. This should be investigated further within a prospective trial.

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Publication Details

Journal
Clinical Oncology
Published
2025-04-22
DOI
https://doi.org/10.1016/j.clon.2025.103847
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Hypo-Fractionated Radiotherapy to the Cavity for Resected Brain Metastases: A UK Series

Rovel Colaco, C.L. Barker, Susanna Meade, Thomas S Shane et al.
Clinical Oncology
Brain Metastases and Treatment
article

Hypo-Fractionated Radiotherapy to the Cavity for Resected Brain Metastases: A UK Series

Rovel Colaco, C.L. Barker, Susanna Meade, Thomas S Shane, Paul Sanghera, M. Jameson, Helen Benghiat, Carol S. Hodgson, Jennifer King
article en

Abstract

In this multicentre series of postoperative hypo-fractionated radiotherapy to the surgical cavity following resection of a brain metastasis, we demonstrated good rates of local control, with low risk of LMD and RN. Therefore, this radiotherapy regimen is a reasonable alternative to cavity SRS in patients with large cavity volumes or complete gross total resection within the UK. This should be investigated further within a prospective trial.

Clinical OncologyVol. 43
Queen Elizabeth Hospital Birmingham (GB), Edwards (United Kingdom) (GB), The Christie NHS Foundation Trust (GB)
Zero hunger
Openalex Percentile: Top 87%
Brain Metastases and Treatment
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Hypo-Fractionated Radiotherapy to the Cavity for Resected Brain Metastases: A UK Series — Rovel Colaco, C.L. Barker, et al. · Clinical Oncology (2025) | TGRS Research Map | TGRS