Early onset gastric cancer: clinical and molecular insights into a rising epidemic among younger adults

This study underscores the aggressive nature of EOGC, highlighting its advanced-stage presentation, poor survival, and distinct molecular pathways. The high prevalence of <i>H. pylori</i> infection, obesity, and smoking reinforces the need for targeted prevention strategies. Given its rising incidence and late-stage diagnosis, risk-based screening, optimized treatment protocols, and novel therapeutic strategies are crucial for improving patient outcomes.