Visible-Light-Induced 4CzIPN-Catalyzed Alkylamination of Alkenes via Cyclobutanone Oxime Esters and Anilines
We disclosed an organophotoredox-catalyzed three-component oxidative radical-polar crossover strategy for constructing 1,2-alkylamination products. Cycloketone oxime derivatives were used as cyanoalkyl radical precursors and anilines were used as the nucleophiles. This facile protocol shows a good reaction yield and broad substrate scope.
Authors
- Li Guo (ORCID: https://orcid.org/0000-0003-3821-4058)
- Zeyu Tian (ORCID: https://orcid.org/0000-0002-1661-7860)
- Jianghong Liu (ORCID: https://orcid.org/0000-0002-8405-6153)
- Tianle Huang (ORCID: https://orcid.org/0009-0009-0184-7899)
- Zhongzhen Yang (ORCID: https://orcid.org/0000-0002-3963-3847)
- Yong Wu (ORCID: https://orcid.org/0000-0003-0719-4963)
- Hai Li (ORCID: https://orcid.org/0000-0002-9659-1153)
- Zhen-Ye Wu
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1021/acs.joc.4c02172
- Citations
- 2
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Department of Science and Technology of Sichuan Province