Bone metaplasia in gallbladder lithiasis: an astonishing clinical phenomenon of a rare case

We present a rare case of acute cholecystitis in a 51-year-old patient. The gallbladder exhibited bone metaplasia, a condition infrequently observed in clinical practice. Acute cholecystitis was confirmed through clinical, radiological, and biological investigations, and the patient underwent cholecystectomy. Histopathological analysis of the surgical specimen revealed bone metaplasia in the gallbladder wall, a phenomenon associated with chronic inflammation due to gallstones. This article highlights the significance of post-surgical histopathological evaluation and discusses follow-up options for such rare conditions.