Oligoclonal IgM band patterns in multiple sclerosis: A two-center study
Our data confirm that CSF OCMB marks poor prognosis in MS. However, both OCMB pattern #4 and pattern #2, with different strength prediction, might be useful to stratify pwMS deserving more aggressive treatments, although the stratification could be achieved in the near future with more standardized and easily measurable biomarkers (e.g., serum neurofilaments).
Authors
- Matteo Gastaldi (ORCID: https://orcid.org/0000-0003-2288-2000)
- Luca Pio Dicembre
- Antonio Uccelli (ORCID: https://orcid.org/0000-0002-2008-6038)
- Elisabetta Capello (ORCID: https://orcid.org/0000-0003-1356-0966)
- Matilde Inglese (ORCID: https://orcid.org/0000-0002-9610-0297)
- Elisabetta Zardini (ORCID: https://orcid.org/0000-0002-2738-3668)
- Francesco Di Masi (ORCID: https://orcid.org/0009-0000-7048-6307)
- Davide Visigalli (ORCID: https://orcid.org/0000-0002-1118-5341)
- Elena Colombo (ORCID: https://orcid.org/0000-0002-5265-5055)
- Diego Franciotta (ORCID: https://orcid.org/0000-0002-3014-3913)
- Sabrina Al Qudsi
Institutions
- University of Pavia (IT)
- Ospedale Santa Chiara (IT)
- Fondazione Istituto Neurologico Nazionale Casimiro Mondino (IT)
- Urology Foundation (GB)
- Ospedale Policlinico San Martino (IT)
Publication Details
- Journal
- Journal of Neuroimmunology
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1016/j.jneuroim.2025.578622
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94