Splenic Embolization for Primary Immune Thrombocytopenia Complicated With Intracranial Hemorrhage—Case Report of 2 Patients

This case report describes the management of 2 pediatric patients with immune thrombocytopenia (ITP) complicated by intracranial hemorrhage. Case 1 involves a 16-year-old who was found to have an acute intracerebral bleed. Partial splenic embolization was performed, which led to improved platelet count and clinical stability. Case 2 details an 8-year-old presenting with a large frontal hematoma with clinical and radiologic signs of herniation. Following complete splenic embolization, his platelet levels rose sufficiently to undergo a successful craniectomy. These cases emphasize the potential role of splenic embolization as an innovative intervention in cases of pediatric ITP with life-threatening bleeding.