Treatment of Presumptive Rejection After Orthotopic Pig‐to‐Baboon Cardiac Xenotransplantation
As we transition to the clinical application of gene-edited pig cardiac xenotransplantation, the ability to treat rejection is of vital importance. The optimal treatment for rejection remains uncertain but we suggest that systemic complement inhibition is important.
Authors
- Sriram Chitta (ORCID: https://orcid.org/0000-0002-2979-9560)
- Joe H. Simmons (ORCID: https://orcid.org/0000-0003-1815-6831)
- David C. Cleveland (ORCID: https://orcid.org/0000-0002-7954-3512)
- Chace Mitchell (ORCID: https://orcid.org/0000-0002-1578-726X)
- David K.C. Cooper (ORCID: https://orcid.org/0000-0003-4149-5452)
- Sarah J. Neal Webb (ORCID: https://orcid.org/0000-0001-9393-3528)
- John D. Cleveland
Institutions
- University of Southern California (US)
- Children's Hospital of Los Angeles (US)
- The University of Texas MD Anderson Cancer Center (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Xenotransplantation
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/xen.70044
- Citations
- 1
- Primary Topic
- Xenotransplantation and immune response
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Institutes of Health
- University of Texas MD Anderson Cancer Center