Clinical potential and experimental validation of prognostic genes in hepatocellular carcinoma revealed by risk modeling utilizing single cell and transcriptome constructs
This study successfully identified eight prognostic genes (MCM10, CEP55, KIF18A, ORC6, KIF23, CDC45, CDT1, and PLK4), which provided new directions for exploring the potential pathogenesis and clinical treatment research of HCC.
Authors
- Yu Zhang (ORCID: https://orcid.org/0000-0002-9191-7708)
- Zhenzhen Jiang (ORCID: https://orcid.org/0000-0002-1075-5306)
- Xiaoxiao Lu (ORCID: https://orcid.org/0000-0001-8972-431X)
- Jian Xu (ORCID: https://orcid.org/0000-0002-0548-8477)
- Hao Zhang (ORCID: https://orcid.org/0000-0002-1850-0770)
- Xu Wang (ORCID: https://orcid.org/0000-0002-2619-9463)
- Hang Deng (ORCID: https://orcid.org/0000-0001-5784-996X)
- Jun Gong (ORCID: https://orcid.org/0000-0001-8713-1406)
- Yao Zhou (ORCID: https://orcid.org/0009-0008-7304-6647)
- Y. R. Hou
Institutions
- North Sichuan Medical University (CN)
- University of Electronic Science and Technology of China (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.3389/fimmu.2025.1541252
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52